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PTRF (CAVIN1) (NM_012232) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC209277L3V
- LentiORF®
-
Lenti ORF particles, PTRF (Myc-DDK tagged) - Human polymerase I and transcript release factor (PTRF), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
| Product Data | |
| Product Name | PTRF (CAVIN1) (NM_012232) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CAVIN; cavin-1; CGL4; FKSG13; PTRF |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_012232 |
| ORF Size | 1170 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209277).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_012232.2 |
| RefSeq Size | 3580 bp |
| RefSeq ORF | 1173 bp |
| Locus ID | 284119 |
| Protein Families | Transcription Factors |
| MW | 43.3 kDa |
| Gene Summary | This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009] |
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