RASGRP1 (NM_005739) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212473L2V

  • LentiORF®

Lenti ORF particles, RASGRP1 (mGFP-tagged) - Human RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name RASGRP1 (NM_005739) Human Tagged ORF Clone Lentiviral Particle
Synonyms CALDAG-GEFI; CALDAG-GEFII; IMD64; RASGRP
Vector pLenti-C-mGFP
ACCN NM_005739
ORF Size 2391 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC212473).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_005739.2
RefSeq Size 5048 bp
RefSeq ORF 2394 bp
Locus ID 10125
Domains RasGEFN, RasGEF, EFh, DAG_PE-bind
Protein Pathways MAPK signaling pathway, T cell receptor signaling pathway
MW 90.4 kDa
Gene Summary This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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