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PRDM16 (NM_022114) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC214026L4V
- LentiORF®
-
Lenti ORF particles, PRDM16 (mGFP-tagged) - Human PR domain containing 16 (PRDM16), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
| Product Data | |
| Product Name | PRDM16 (NM_022114) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CMD1LL; KMT8F; LVNC8; MEL1; PFM13 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_022114 |
| ORF Size | 3828 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214026).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_022114.2 |
| RefSeq Size | 8726 bp |
| RefSeq ORF | 3831 bp |
| Locus ID | 63976 |
| MW | 140.1 kDa |
| Gene Summary | The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
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