Human Aconitase 2 (ACO2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ACO2
Locus ID	50
Kit Components	GA100038G1, Aconitase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100038G2, Aconitase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100038G3, Aconitase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001098
Synonyms	ACONM; HEL-S-284; ICRD; OCA8; OPA9
Summary	The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]

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