Human 15 Lipoxygenase 2 (ALOX15B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ALOX15B
Locus ID	247
Kit Components	GA100171G1, 15 Lipoxygenase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100171G2, 15 Lipoxygenase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100171G3, 15 Lipoxygenase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039130, NM_001039131, NM_001141
Synonyms	15-LOX-2
Summary	This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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