Human cIAP1 (BIRC2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BIRC2
Locus ID	329
Kit Components	GA100230G1, cIAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100230G2, cIAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100230G3, cIAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166, NM_001256163, NM_001256166
Synonyms	API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
Summary	The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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