Human ARHGAP6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP6
Locus ID	395
Kit Components	GA100285G1, ARHGAP6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100285G2, ARHGAP6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100285G3, ARHGAP6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001174, NM_001287242, NM_006125, NM_013422, NM_013423, NM_013427, NR_109776
Synonyms	OTTHUMP00000022913; OTTHUMP00000022915; OTTHUMP00000022916; OTTHUMP00000022918; Rho-type GTPase-activating protein RhoGAPX-1; RHOGAP6; RHOGAP6, rhoGAPX-1; RHOGAPX-1; Rho GTPase activating protein 6
Summary	This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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