Human RHOH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RHOH
Locus ID	399
Kit Components	GA100289G1, RHOH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100289G2, RHOH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100289G3, RHOH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278359, NM_001278360, NM_001278361, NM_001278362, NM_001278363, NM_001278364, NM_001278365, NM_001278366, NM_001278367, NM_001278368, NM_001278369, NM_004310
Synonyms	ARHH; TTF
Summary	The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]

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