Human BDNF activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BDNF
Locus ID	627
Kit Components	GA100426G1, BDNF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100426G2, BDNF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100426G3, BDNF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143805, NM_001143806, NM_001143807, NM_001143808, NM_001143809, NM_001143810, NM_001143811, NM_001143812, NM_001143813, NM_001143814, NM_001143815, NM_001143816, NM_001709, NM_170731, NM_170732, NM_170733, NM_170734, NM_170735
Synonyms	ANON2; BULN2
Summary	This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]

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