Human C1QC activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C1QC
Locus ID	714
Kit Components	GA100494G1, C1QC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100494G2, C1QC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100494G3, C1QC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001114101, NM_172369, NM_001347619, NM_001347620
Synonyms	C1Q-C; C1QG
Summary	This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]

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