Human C1R activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C1R
Locus ID	715
Kit Components	GA100495G1, C1R gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100495G2, C1R gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100495G3, C1R gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001733, NM_001354346
Synonyms	complement component 1, r subcomponent
Summary	This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]

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