Human Calcitonin (CALCA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CALCA
Locus ID	796
Kit Components	GA100557G1, Calcitonin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100557G2, Calcitonin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100557G3, Calcitonin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033952, NM_001033953, NM_001741, NR_125898
Synonyms	CALC1; CGRP; CGRP-I; CGRP1; CT; KC; PCT
Summary	This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]

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