Human CD63 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CD63
Locus ID	967
Kit Components	GA100688G1, CD63 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100688G2, CD63 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100688G3, CD63 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040034, NM_001257389, NM_001257390, NM_001257391, NM_001257392, NM_001257400, NM_001257401, NM_001257405, NM_001267698, NM_001780
Synonyms	LAMP-3; ME491; MLA1; OMA81H; TSPAN30
Summary	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

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