Human CDC2L1 (CDK11B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDK11B
Locus ID	984
Kit Components	GA100701G1, CDC2L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100701G2, CDC2L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100701G3, CDC2L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291345, NM_001787, NM_033486, NM_033487, NM_033488, NM_033489, NM_033490, NM_033491, NM_033492, NM_033493
Synonyms	CDC2L1; CDK11; CDK11-p46; CDK11-p58; CDK11-p110; CLK-1; p58; p58CDC2L1; p58CLK-1; PITSLREA
Summary	This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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