Human Leukotriene B4 Receptor (LTB4R) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LTB4R
Locus ID	1241
Kit Components	GA100876G1, Leukotriene B4 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100876G2, Leukotriene B4 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100876G3, Leukotriene B4 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000752, NM_001143919, NM_181657
Synonyms	BLT1; BLTR; CMKRL1; GPR16; LTB4R1; LTBR1; P2RY7; P2Y7
Summary	Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.[UniProtKB/Swiss-Prot Function]

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