Human Collagen X (COL10A1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COL10A1
Locus ID	1300
Kit Components	GA100914G1, Collagen X gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100914G2, Collagen X gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100914G3, Collagen X gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000493
Synonyms	collagen, type X, alpha 1; collagen X, alpha-1 polypeptide; OTTHUMP00000017049; OTTHUMP00000040411; Schmid metaphyseal chondrodysplasia; type X collagen alpha 1
Summary	This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]

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