Human CRAT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CRAT
Locus ID	1384
Kit Components	GA100970G1, CRAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100970G2, CRAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100970G3, CRAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000755, NM_001257363, NM_004003, NM_144782, NR_028048, NM_001346546, NM_001346547, NM_001346548, NM_001346549
Synonyms	CAT1
Summary	This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]

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