Human Cathepsin H (CTSH) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTSH
Locus ID	1512
Kit Components	GA101070G1, Cathepsin H gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101070G2, Cathepsin H gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101070G3, Cathepsin H gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319137, NM_004390, NM_148979
Synonyms	ACC-4; ACC-5; ACC4; ACC5; CPSB
Summary	The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

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