Human CX3CR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CX3CR1
Locus ID	1524
Kit Components	GA101079G1, CX3CR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101079G2, CX3CR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101079G3, CX3CR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001171171, NM_001171172, NM_001171174, NM_001337
Synonyms	CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
Summary	Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

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