Human Alpha Dystroglycan (DAG1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DAG1
Locus ID	1605
Kit Components	GA101129G1, Alpha Dystroglycan gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101129G2, Alpha Dystroglycan gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101129G3, Alpha Dystroglycan gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001165928, NM_001177634, NM_001177635, NM_001177636, NM_001177637, NM_001177638, NM_001177639, NM_001177640, NM_001177641, NM_001177642, NM_001177643, NM_001177644, NM_004393
Synonyms	156DAG; A3a; AGRNR; DAG; MDDGC7; MDDGC9
Summary	This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015]

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