Human DHPS activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DHPS
Locus ID	1725
Kit Components	GA101196G1, DHPS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101196G2, DHPS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101196G3, DHPS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001206974, NM_001930, NM_013406, NM_013407, NR_038192, NM_001369691, NM_001369693, NR_161467, NR_161469, NM_001369692, NR_161468
Synonyms	DHS; DS; MIG13
Summary	This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011]

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