Human SAP102 (DLG3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DLG3
Locus ID	1741
Kit Components	GA101210G1, SAP102 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101210G2, SAP102 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101210G3, SAP102 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166278, NM_020730, NM_021120
Synonyms	MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR
Summary	This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

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