Human DNMT3A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNMT3A
Locus ID	1788
Kit Components	GA101244G1, DNMT3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101244G2, DNMT3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101244G3, DNMT3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320892, NM_001320893, NM_022552, NM_153759, NM_175629, NM_175630, NR_135490
Synonyms	DNMT3A2; M.HsaIIIA; TBRS
Summary	CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]

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