Human Dopamine D2 Receptor (DRD2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DRD2
Locus ID	1813
Kit Components	GA101266G1, Dopamine D2 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101266G2, Dopamine D2 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101266G3, Dopamine D2 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000795, NM_016574
Synonyms	D2DR; D2R
Summary	This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

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