Human TSC22D3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TSC22D3
Locus ID	1831
Kit Components	GA101282G1, TSC22D3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101282G2, TSC22D3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101282G3, TSC22D3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001015881, NM_001318468, NM_001318470, NM_004089, NM_198057
Synonyms	DIP; DSIPI; GILZ; TSC-22R
Summary	This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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