Human EDG1 (S1PR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	S1PR1
Locus ID	1901
Kit Components	GA101324G1, EDG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101324G2, EDG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101324G3, EDG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001400, NM_001320730
Synonyms	CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1
Summary	The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

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