Human Endothelin A Receptor (EDNRA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EDNRA
Locus ID	1909
Kit Components	GA101330G1, Endothelin A Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101330G2, Endothelin A Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101330G3, Endothelin A Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166055, NM_001256283, NM_001957, NR_028596, NR_045958, NM_001354797, NR_148963, NR_148964
Synonyms	ET-A; ETA; ETA-R; ETAR; ETRA; hET-AR
Summary	This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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