Human EIF4B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EIF4B
Locus ID	1975
Kit Components	GA101368G1, EIF4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101368G2, EIF4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101368G3, EIF4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001300821, NM_001330654, NM_001417
Synonyms	EIF-4B; PRO1843
Summary	Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.[UniProtKB/Swiss-Prot Function]

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