Human EIF4EBP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EIF4EBP2
Locus ID	1979
Kit Components	GA101371G1, EIF4EBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101371G2, EIF4EBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101371G3, EIF4EBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004096
Synonyms	4EBP2; PHASII
Summary	This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]

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