Human CD32B (FCGR2B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FCGR2B
Locus ID	2213
Kit Components	GA101550G1, CD32B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101550G2, CD32B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101550G3, CD32B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002273, NM_001002274, NM_001002275, NM_001190828, NM_004001
Synonyms	CD32; CD32B; FCG2; FCGR2; IGFR2
Summary	The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

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