Human FGF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FGF1
Locus ID	2246
Kit Components	GA101569G1, FGF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101569G2, FGF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101569G3, FGF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000800, NM_001144892, NM_001144934, NM_001144935, NM_001257205, NM_001257206, NM_001257207, NM_001257208, NM_001257209, NM_001257210, NM_001257211, NM_001257212, NM_033136, NM_033137, NR_026695, NR_026696, NM_001354951, NM_001354952, NM_001354953, NM_001354954, NM_001354955, NM_001354956, NM_001354957, NM_001354958, NM_001354959, NM_001354961, NM_001354962, NM_001354963, NM_001354964
Synonyms	AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1
Summary	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

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