Human FKBP51 (FKBP5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FKBP5
Locus ID	2289
Kit Components	GA101602G1, FKBP51 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101602G2, FKBP51 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101602G3, FKBP51 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145775, NM_001145776, NM_001145777, NM_004117
Synonyms	AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10
Summary	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

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