Human Ku70 (XRCC6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XRCC6
Locus ID	2547
Kit Components	GA101691G1, Ku70 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101691G2, Ku70 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101691G3, Ku70 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001288976, NM_001288977, NM_001288978, NM_001469
Synonyms	CTC75; CTCBF; G22P1; KU70; ML8; TLAA
Summary	The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.