Human GABA A Receptor alpha 5 (GABRA5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GABRA5
Locus ID	2558
Kit Components	GA101701G1, GABA A Receptor alpha 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101701G2, GABA A Receptor alpha 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101701G3, GABA A Receptor alpha 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000810, NM_001165037
Synonyms	MGC138184
Summary	GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]

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