Human GABA A Receptor beta 3 (GABRB3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GABRB3
Locus ID	2562
Kit Components	GA101705G1, GABA A Receptor beta 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101705G2, GABA A Receptor beta 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101705G3, GABA A Receptor beta 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000814, NM_001191320, NM_001191321, NM_001278631, NM_021912, NR_103801
Synonyms	ECA5; EIEE43
Summary	This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]

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