Human KAT2A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KAT2A
Locus ID	2648
Kit Components	GA101767G1, KAT2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101767G2, KAT2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101767G3, KAT2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021078
Synonyms	GCN5; GCN5L2; hGCN5; PCAF-b
Summary	KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]

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