Human GIP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GIP
Locus ID	2695
Kit Components	GA101801G1, GIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101801G2, GIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101801G3, GIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004123
Synonyms	gastric inhibitory polypeptide; glucose-dependent insulinotropic polypeptide
Summary	This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]

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