Human GRK4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRK4
Locus ID	2868
Kit Components	GA101928G1, GRK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101928G2, GRK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101928G3, GRK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001004056, NM_001004057, NM_005307, NM_182982, NM_001350173
Synonyms	GPRK2L; GPRK4; GRK4a; IT11
Summary	This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

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