Human GRO alpha (CXCL1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CXCL1
Locus ID	2919
Kit Components	GA101974G1, GRO alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101974G2, GRO alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101974G3, GRO alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001511, NR_046035
Synonyms	FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
Summary	This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]

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