Human GUCY1A1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GUCY1A1
Locus ID	2982
Kit Components	GA102023G1, GUCY1A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102023G2, GUCY1A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102023G3, GUCY1A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000856, NM_001130682, NM_001130683, NM_001130684, NM_001130685, NM_001130686, NM_001130687, NM_001256449
Synonyms	GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; MYMY6
Summary	Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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