Human HMGCL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HMGCL
Locus ID	3155
Kit Components	GA102150G1, HMGCL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102150G2, HMGCL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102150G3, HMGCL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000191, NM_001166059
Synonyms	HL
Summary	The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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