Human HOXA9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HOXA9
Locus ID	3205
Kit Components	GA102190G1, HOXA9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102190G2, HOXA9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102190G3, HOXA9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002142, NM_152739
Synonyms	ABD-B; homeo box A9; homeobox A9; homeobox protein HOXA9; homeodomain protein HOXA9; HOX1; HOX1, ABD-B, HOX1G, HOX1.7, MGC1934; HOX1.7; HOX1G; MGC1934
Summary	In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011]

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