Human HOXB3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HOXB3
Locus ID	3213
Kit Components	GA102197G1, HOXB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102197G2, HOXB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102197G3, HOXB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002146, NM_001330322, NM_001330323
Synonyms	Hox-2.7; HOX2; HOX2G
Summary	This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008]

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