Human ICT1 (MRPL58) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MRPL58
Locus ID	3396
Kit Components	GA102304G1, ICT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102304G2, ICT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102304G3, ICT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001303265, NM_001545
Synonyms	DS-1; DS1; ICT1; MRP-L58
Summary	The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

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