Human IFNAR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IFNAR1
Locus ID	3454
Kit Components	GA102339G1, IFNAR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102339G2, IFNAR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102339G3, IFNAR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000629
Synonyms	AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC
Summary	The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]

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