Human IFNGR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IFNGR1
Locus ID	3459
Kit Components	GA102343G1, IFNGR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102343G2, IFNGR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102343G3, IFNGR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000416, NM_001363527, NM_001363526
Synonyms	CD119; IFNGR; IMD27A; IMD27B
Summary	This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

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