Human IFNGR2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IFNGR2
Locus ID	3460
Kit Components	GA102344G1, IFNGR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102344G2, IFNGR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102344G3, IFNGR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005534, NM_001329128
Synonyms	AF-1; IFGR2; IFNGT1; IMD28
Summary	This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]

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