Human ALS (IGFALS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IGFALS
Locus ID	3483
Kit Components	GA102352G1, ALS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102352G2, ALS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102352G3, ALS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146006, NM_004970, NR_027389
Synonyms	ACLSD; ALS
Summary	The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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