Human ING1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ING1
Locus ID	3621
Kit Components	GA102425G1, ING1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102425G2, ING1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102425G3, ING1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001267728, NM_005537, NM_198217, NM_198218, NM_198219
Synonyms	p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
Summary	This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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