Human CD18 (ITGB2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ITGB2
Locus ID	3689
Kit Components	GA102478G1, CD18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102478G2, CD18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102478G3, CD18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000211, NM_001127491, NM_001303238
Synonyms	CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Summary	This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

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